FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  ALTA BIOPHARMA PARTNERS III LP
2. Date of Event Requiring Statement (Month/Day/Year)
10/11/2013
3. Issuer Name and Ticker or Trading Symbol
CymaBay Therapeutics, Inc. [NONE]
(Last)
(First)
(Middle)
ONE EMBARCADERO CENTER, SUITE 3700
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

SAN FRANCISCO, CA 94111
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 64,501 (1)
I
Alta BioPharma Partners III GmbH & Co. Beteiligungs KG (1)
Common Stock 960,433 (2)
D
 
Common Stock 23,668 (3)
I
Alta Embarcadero BioPharma Partners III, LLC (3)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Warrants (right to buy) 09/30/2013 09/30/2018 Common Stock 4,613 (1) $ 5.75 I Alta BioPharma Partners III GmbH & Co. Beteiligungs KG (1)
Warrants (right to buy) 09/30/2013 09/30/2018 Common Stock 68,693 (2) $ 5.75 D  
Warrants (right to buy) 09/30/2013 09/30/2018 Common Stock 1,692 (3) $ 5.75 I Alta Embarcadero BioPharma Partners III, LLC (3)

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
ALTA BIOPHARMA PARTNERS III LP
ONE EMBARCADERO CENTER
SUITE 3700
SAN FRANCISCO, CA 94111
    X    
ALTA BIOPHARMA PARTNERS III GMBH & CO BETEILIGUNGS KG
ONE EMBARCADERO CENTER
SUITE 3700
SAN FRANCISCO, CA 94111
    X    
ALTA EMBARCADERO BIOPHARMA PARTNERS III LLC
ONE EMBARCADERO CENTER
SUITE 3700
SAN FRANCISCO, CA 94111
    X    

Signatures

/s/ Edward E. Penhoet 10/11/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The securities are held by Alta BioPharma Partners III GmbH & Co. Beteiligungs KG ("ABP III KG"). Alta BioPharma Management Partners III, LLC ("ABMP") is the managing imited partner of ABP III KG. ABMP disclaims beneficial ownership of these securities except to the extent of any pecuniary interest therein.
(2) The securities are held by Alta BioPharma Partners III, L.P. ("ABP III"). ABMP is the general partner of ABP III. ABMP disclaims beneficial ownership of these securities except to the extent of any pecuniary interest therein.
(3) The securities are held by Alta Embarcadero BioPharma Partners III, LLC ("AEBP III"). ABMP is the manager of AEBP III. ABMP disclaims beneficial ownership of these securities except to the extent of any pecuniary interest therein.

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